Mathematics and Science
- Matrix (biology), the material or tissue between cells in which more specialized structures are embedded
- Matrix (chemical analysis), the non-analyte components of a sample
- Matrix (geology), the fine-grained material in which larger objects are embedded
- Matrix (mathematics), a rectangular array of numbers, symbols or expressions
- Matrix isolation, an experimental technique in chemistry and physics
- Harris matrix, an archeological tool
- Metal matrix, material used in a metal matrix composite
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