Usp15

USP15

Identifiers Symbols USP15; UNPH-2; UNPH4 External IDs OMIM: 604731 MGI: 101857 HomoloGene: 101542 GeneCards: USP15 Gene EC number 3.4.19.12

Gene Ontology
Molecular function	• cysteine-type endopeptidase activity • ubiquitin thiolesterase activity • ubiquitin-specific protease activity • transforming growth factor beta receptor binding • SMAD binding
Cellular component	• nucleus • cytoplasm
Biological process	• ubiquitin-dependent protein catabolic process • transforming growth factor beta receptor signaling pathway • protein deubiquitination • BMP signaling pathway • negative regulation of transforming growth factor beta receptor signaling pathway • monoubiquitinated protein deubiquitination • pathway-restricted SMAD protein phosphorylation
Sources: Amigo / QuickGO

Orthologs Species Human Mouse Entrez 9958 14479 Ensembl ENSG00000135655 ENSMUSG00000020124 UniProt Q9Y4E8 Q8R5H1 RefSeq (mRNA) NM_001252078 NM_027604 RefSeq (protein) NP_001239007 NP_081880 Location (UCSC) Chr 12:
62.65 – 62.81 Mb Chr 10:
123.11 – 123.2 Mb PubMed search

Ubiquitin carboxyl-terminal hydrolase 15 is an enzyme that in humans is encoded by the USP15 gene.