Ubiquitin is a small regulatory protein that has been found in almost all tissues (ubiquitously) of eukaryotic organisms. It directs proteins to compartments in the cell, including the proteasome which destroys and recycles proteins.
| Ubiquitin family | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| A diagram of ubiquitin. The seven lysine sidechains are shown in orange. | |||||||||
| Identifiers | |||||||||
| Symbol | ubiquitin | ||||||||
| Pfam | PF00240 | ||||||||
| InterPro | IPR000626 | ||||||||
| PROSITE | PDOC00271 | ||||||||
| SCOP | 1aar | ||||||||
| SUPERFAMILY | 1aar | ||||||||
|
|||||||||
Ubiquitin can be attached to proteins and label them for destruction. This discovery won the Nobel Prize for chemistry in 2004.
Ubiquitin tags can also direct proteins to other locations in the cell, where they control other protein and cell mechanisms.
Read more about Ubiquitin: Identification, The Protein, Genes, Origins, Ubiquitination (ubiquitylation), Function and Variety of Ubiquitin Modifications, Ubiquitin-like Modifiers, Prokaryotic Ubiquitin-like Protein (Pup), Human Proteins Containing Ubiquitin Domain, Related Proteins, Prediction of Ubiquitination