QU, Qu or qu may refer to:
- Qu (programming language), a computer programming language
- QU (album), an album by the American band Sherwood
- Qu (poetry), a Chinese type of sung poetry
- Qu (surname), a Chinese surname
- qu (coin), a 16th Century Elizabethan coin, almost worthless even at time of issue (cf full Oxford English Dictionary)
- qu (digraph), a digraph used in several languages.
- Qu, a race of gourmands from the Square Enix console role-playing game Final Fantasy IX
- Qu County, county in Sichuan, China
- qu, ISO 639-1 code for Quechua, a Native American language of South America
- East African Airlines IATA airline designator
- another name for the plant Myrocarpus frondosus
- a member of the History Monks in Terry Pratchett's Discworld novels
- Districts in the People's Republic of China and the Republic of China
In academia:
- Queensland University, Brisbane, Queensland, Australia
- Queen's University, Kingston, Ontario, Canada
- Quincy University, Quincy, Illinois, United States
- Quinnipiac University, Hamden, Connecticut, United States
- Qassim University, Qassim, Saudi Arabia