Prairie Fire can refer to:
- A wildfire in grassland
- A supercomputer at the University of Nebraska-Lincoln
- The mascot for Knox College of Galesburg, Illinois
- Saskatchewan Prairie Fire, of the Rugby Canada Super League
- Prairie Fire, a Canadian literary magazine
- Prairie Fire (mixed drink)
- A book by the radical group known as the Weather Underground Organization
- A painting by Blackbear Bosin
- Prairie Fire (TV series), a 15+ season running news magazine / documentary program produced by WILL, a public broadcasting station owned by the University of Illinois at Urbana-Champaign
- Operation Prairie Fire, US military strikes against Libya in 1986.
- Operation Prairie Fire, a US Studies and Observations Group (SOG) reconnaissance mission into Laos on February 20, 1968.
Famous quotes related to prairie fire:
“The junior senator from Wisconsin, by his reckless charges, has so preyed upon the fears and hatreds and prejudices of the American people that he has started a prairie fire which neither he nor anyone else may be able to control.”
—J. William Fulbright (b. 1905)