Computing
- Pipeline (computing), a set of data processing elements connected in series
- Pipeline (software), a chain of processes or other data processing entities
- Pipeline (Unix), a set of processes chained by their standard streams
- Anonymous pipe and named pipe, a one-way communication channel used for inter-process communication
- Vertical bar, sometimes called "pipe", the ASCII character "
|" - "PHY Interface for PCI Express" (PIPE), the name of a specification for the PCI Express physical layer
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