Perryville may refer to a location in the United States:
- Perryville, Alaska
- Perryville, Arkansas
- Perryville, Kentucky
- The Battle of Perryville, in the American Civil War
- Perryville, Maryland
- Perryville, Missouri
- Perryville (McAlester, Oklahoma) on the list of NRHPs in Oklahoma
- Arizona State Prison Complex - Perryville, a prison in Goodyear, Maricopa County, Arizona