Knob Creek can refer to:
- Any of several streams by that name.
- Knob Creek, Arkansas in Izard County
- Knob Creek, Bullitt County, Kentucky in Bullitt County
- Knob Creek, Graves County, Kentucky in Graves County
- Knob Creek, North Carolina in Cleveland County
- Knob Creek, Tennessee in Lauderdale County
- Knob Creek, Tennessee in Lawrence County
- Knob Creek, Tennessee in Sevier County
- Knob Creek, Tennessee in Washington County
- Knob Creek Farm, boyhood home of Abraham Lincoln, a unit of Abraham Lincoln Birthplace National Historic Site
- Knob Creek (bourbon), a small batch bourbon whiskey made by, and a registered trademark of, Jim Beam Brands Co.
- Knob Creek Gun Range, a shooting range in Bullitt County, Kentucky.
Famous quotes containing the word creek:
“The only law was that enforced by the Creek Lighthorsemen and the U.S. deputy marshals who paid rare and brief visits; or the “two volumes of common law” that every man carried strapped to his thighs.”
—State of Oklahoma, U.S. relief program (1935-1943)