History
Harold Urey discovered the isotope deuterium in 1931 and was later able to concentrate it in water. Urey's mentor Gilbert Newton Lewis isolated the first sample of pure heavy water by electrolysis in 1933. George de Hevesy and Hoffer used heavy water in 1934 in one of the first biological tracer experiments, to estimate the rate of turnover of water in the human body. The history of large-quantity production and use of heavy water in early nuclear experiments is given below. Emilian Bratu and Otto Redlich studied the autodissociation of heavy water in 1934.
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