Growth Factor - Classes of Growth Factors

Classes of Growth Factors

Individual growth factor proteins tend to occur as members of larger families of structurally and evolutionarily related proteins. There are many families, which are listed below:

This list is incomplete; you can help by expanding it.
  • Adrenomedullin (AM)
  • Angiopoietin (Ang)
  • Autocrine motility factor
  • Bone morphogenetic proteins (BMPs)
  • Brain-derived neurotrophic factor (BDNF)
  • Epidermal growth factor (EGF)
  • Erythropoietin (EPO)
  • Fibroblast growth factor (FGF)
  • Glial cell line-derived neurotrophic factor (GDNF)
  • Granulocyte colony-stimulating factor (G-CSF)
  • Granulocyte macrophage colony-stimulating factor (GM-CSF)
  • Growth differentiation factor-9 (GDF9)
  • Hepatocyte growth factor (HGF)
  • Hepatoma-derived growth factor (HDGF)
  • Insulin-like growth factor (IGF)
  • Migration-stimulating factor
  • Myostatin (GDF-8)
  • Nerve growth factor (NGF) and other neurotrophins
  • Platelet-derived growth factor (PDGF)
  • Thrombopoietin (TPO)
  • Transforming growth factor alpha(TGF-α)
  • Transforming growth factor beta(TGF-β)
  • Tumor_necrosis_factor-alpha(TNF-α)
  • Vascular endothelial growth factor (VEGF)
  • Wnt Signaling Pathway
  • placental growth factor (PlGF)
  • (FBS)
  • IL-1- Cofactor for IL-3 and IL-6. Activates T cells.
  • IL-2- T-cell growth factor. Stimulates IL-1 synthesis. Activates B-cells and NK cells.
  • IL-3- Stimulates production of all non-lymphoid cells.
  • IL-4- Growth factor for activated B cells, resting T cells, and mast cells.
  • IL-5- Induces differentiation of activated B cells and eosinophils.
  • IL-6- Stimulates Ig synthesis. Growth factor for plasma cells.
  • IL-7- Growth factor for pre-B cells.


Stimulates cell cycle from G0 phase to G1 phase

Read more about this topic:  Growth Factor

Famous quotes containing the words classes of, classes, growth and/or factors:

    “The want of education and moral training is the only real barrier that exists between the different classes of men. Nature, reason, and Christianity recognize no other. Pride may say Nay; but Pride was always a liar, and a great hater of the truth.”
    —Susanna Moodie (1803–1885)

    “The difference between people isn’t in their class, but in themselves. Only from the middle classes one gets ideas, and from the common people—life itself, warmth. You feel their hates and loves.”
    —D.H. (David Herbert)

    “The reality is that zero defects in products plus zero pollution plus zero risk on the job is equivalent to maximum growth of government plus zero economic growth plus runaway inflation.”
    —Dixie Lee Ray (b. 1924)

    “The economic dependence of woman and her apparently indestructible illusion that marriage will release her from loneliness and work and worry are potent factors in immunizing her from common sense in dealing with men at work.”
    —Mary Barnett Gilson (1877–?)