Chrétien may refer to:
- Chrétien de Troyes, 12th century French poet
- Chrétien Le Clercq, 17th century Roman Catholic missionary
- Chrétien-Louis-Joseph de Guignes (1759–1845), French merchant-trader, diplomat and scholar
- Gilles-Louis Chrétien (1754-1811) inventor of the physionotrace
- Chrétien Urhan (1790–1845), French musician and composer
- Henri Chrétien, (1879–1956), French astronomer and inventor
- Jean Chrétien (born 1934), 20th Prime Minister of Canada (serving 1993-2003), and former leader of the Liberal Party of Canada (serving 1990-2003) also:
- Aline Chrétien (born 1936), his wife
- Michel Chrétien (born 1968), his son
- Raymond Chrétien (born 1942), former Canadian ambassador to the United States, his nephew
- Jean-Guy Chrétien (born 1946), Canadian politician
- Jean-Loup Chrétien (born 1938), French astronaut
- Todd Chretien (born 1969), contemporary U.S. activist
- Chrétien (crater), a lunar crater
- William Chretien (born 1916), former American sailor during World War II, Received Purple Heart.
In the French language, Chrétien is the masculine form of 'Christian', as both noun, adjective or adverb.