Adenosine deaminase deficiency, also called ADA deficiency or ADA-SCID, is an autosomal recessive metabolic disorder that causes immunodeficiency. It occurs in fewer than one in 100,000 live births worldwide.
It accounts for about 15% of all cases of severe combined immunodeficiency (SCID).
ADA deficiency may be present in infancy, childhood, adolescense, or adulthood. Age of onset and severity is related to some 29 known genotypes associated with the disorder.
Read more about Adenosine Deaminase Deficiency: Pathophysiology, Genetics, Treatment
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