Jonesboro or Jonesborough is the name of a number of settlements in the United States and the United Kingdom:
USA
- Jonesboro, Arkansas
- Jonesboro massacre, a school shooting incident
- Jonesboro, Georgia, originally Jonesborough
- Jonesboro, Illinois
- Jonesboro, Indiana
- Jonesboro, Louisiana
- Jonesboro, Maine
- Jonesboro, Oregon
- Jonesborough, Tennessee
United Kingdom
- Jonesborough, County Armagh, a small village in Northern Ireland