XLA can mean different things:
- XLA (singer) is a Canadian indie singer
- Microsoft Excel Add-in file format
- Xlib Archive file format.
- XL Associates, a professional services firm.
- XLA is a weight loss supplement.
- Dow XLA elastic fiber, New, olefinic-based fiber inherently resists harsh chemicals, high heat,...
- X-linked agammaglobulinemia, an immune deficiency.
- Excel Airways's ICAO three letter callsign.
- XLA, the ticker symbol on the American Stock Exchange for now-defunct Xclera.com
- Microsoft's videogames downloading service Xbox Live Arcade.
- Cross Linked Acrylic