XC may refer to:

  • Christogram
  • 90 (number) in Roman numerals
  • Cross-country running
  • Cross-country skiing
  • Cross-country cycling
  • Cross-country equestrianism
  • Cross-country paragliding
  • XC, a model of the Ford Falcon
  • Capacitive reactance or XC, a property of a capacitor
  • Xavier College (Melbourne), a school in Australia
  • XC Trains Ltd., the company name of the brand CrossCountry
  • Xylene cyanol, a color marker used in gel electrophoresis
  • Extensible Catalog, the University of Rochester's Project for FRBR model for library metadata
  • XC Programming Language, a concurrent programming language developed by XMOS