Withington is a suburban area of the City of Manchester, in Greater Manchester, England. It lies 4 miles (6.4 km) south of Manchester city centre, about 0.4 miles (0.6 km) south of Fallowfield, 0.5 miles (0.8 km) north-east of Didsbury, and 1 mile (1.6 km) east of Chorlton-cum-Hardy, near the centre-to-south edges of the Greater Manchester Urban Area; in the Manchester Withington parliamentary constituency. Withington is a dormitory village consisting of a resident population slightly over 14,000 people.
In the early 13th century, Withington occupied a feudal estate that included the townships of Withington, Chorlton-cum-Hardy, Moss Side, Rusholme, Burnage, Denton and Haughton, held by the Hathersage, Longford and Tatton families, and within the Manor of Manchester and Hundred of Salford in historic county boundaries of Lancashire.
Withington was largely rural until the mid-nineteenth century, in which it experienced rapid socioeconomic development and urbanisation due to the Industrial Revolution, and Manchester's growing level of industrialisation. Introduced into the inner boundaries of Manchester in 1904, Withington was integrated into the city forty-five years after it gained city status.
Today, the residents of Withington comprise a mixture of families, university students and "young professionals"—often themselves former students. This is in a large part due to its education links—particularly the proximity to the University of Manchester, and Manchester Metropolitan University. As a consequence, Withington is predominantly an area of mixed affluence. It is also a centre for clinical excellence with one of the largest cancer treatment centres in Europe—Christie Hospital—and Withington Community Hospital.