Physiology
At the onset of this condition, fluid outside the cells has an excessively low amount of solutes (such as sodium (hyponatremia) and other electrolytes) in comparison to that inside the cells causing the fluid to shift through (via osmosis) into the cells to balance its concentration. This causes the cells to swell. In the brain, this swelling increases intracranial pressure (ICP). It is this increase in pressure which leads to the first observable symptoms of water intoxication: headache, personality changes, changes in behavior, confusion, irritability, and drowsiness. These are sometimes followed by difficulty breathing during exertion, muscle weakness, twitching, or cramping, nausea, vomiting, thirst, and a dulled ability to perceive and interpret sensory information. As the condition persists papillary and vital signs may result including bradycardia and widened pulse pressure. The cells in the brain may swell to the point where blood flow is interrupted resulting in cerebral edema. Swollen brain cells may also apply pressure to the brain stem causing central nervous system dysfunction. Both cerebral edema and interference with the central nervous system are dangerous and could result in seizures, brain damage, coma or death.
Read more about this topic: Water Intoxication
Famous quotes containing the word physiology:
“A physician’s physiology has much the same relation to his power of healing as a cleric’s divinity has to his power of influencing conduct.”
—Samuel Butler (1835–1902)
“If church prelates, past or present, had even an inkling of physiology they’d realise that what they term this inner ugliness creates and nourishes the hearing ear, the seeing eye, the active mind, and energetic body of man and woman, in the same way that dirt and dung at the roots give the plant its delicate leaves and the full-blown rose.”
—Sean O’Casey (1884–1964)
“Now the twitching stops. Now you are still. We are through with physiology and theology, physics begins.”
—Alfred Döblin (1878–1957)