Vitamin C Megadosage - Possible Adverse Effects

Possible Adverse Effects

Although sometimes considered free of toxicity, there are known side effects from vitamin C intake, and it has been suggested that any administration should require "a medical environment and trained professionals."

  • A genetic condition that results in inadequate levels of the enzyme glucose-6-phosphate dehydrogenase (G6PD) can cause sufferers to develop hemolytic anemia after using intravenous vitamin C treatment. G6PD deficiency test is a common laboratory test.
  • Vitamin C administration can acidify the urine, promoting the precipitation of kidney stones or drugs in the urine.
  • Because oxalic acid is produced in the metabolism of vitamin C, hyperoxaluria can be caused by intravenous administration of ascorbic acid.

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