Usp7

USP7

Identifiers Symbols USP7; HAUSP; TEF1 External IDs OMIM: 602519 MGI: 2182061 HomoloGene: 2592 GeneCards: USP7 Gene EC number 3.4.19.12

Gene Ontology
Molecular function	• p53 binding • cysteine-type endopeptidase activity • ubiquitin thiolesterase activity • ubiquitin-specific protease activity • protein binding • protein C-terminus binding • transcription factor binding • ubiquitin protein ligase binding
Cellular component	• nucleus • cytosol • PML body
Biological process	• transcription-coupled nucleotide-excision repair • ubiquitin-dependent protein catabolic process • multicellular organismal development • maintenance of DNA methylation • protein deubiquitination • virus-host interaction • negative regulation of NF-kappaB transcription factor activity • regulation of sequence-specific DNA binding transcription factor activity
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 7874 252870 Ensembl ENSG00000187555 ENSMUSG00000022710 UniProt Q93009 Q6A4J8 RefSeq (mRNA) NM_003470 NM_001003918 RefSeq (protein) NP_003461 NP_001003918 Location (UCSC) Chr 16:
8.99 – 9.06 Mb Chr 16:
8.69 – 8.79 Mb PubMed search

Ubiquitin-specific-processing protease 7 (USP7) also known as ubiquitin carboxyl-terminal hydrolase 7 or herpesvirus-associated ubiquitin-specific protease (HAUSP) is an enzyme that in humans is encoded by the USP7 gene.