USL may refer to:

Arts and entertainment
  • Underground Sound of Lisbon, a Portuguese dance music project
  • Urban Strawberry Lunch, a Band from Liverpool
  • USL, a music Club in Switzerland
  • Universal Systems Language, a language for system engineering and software development
  • Unix System Laboratories, a defunct American software company
  • University of Louisiana at Lafayette, formerly known as "University of Southwestern Louisiana" (USL), a university in the United States
  • University of Saint Louis Tuguegarao, a private university in the Philippines.
  • University of Sierra Leone, the public university system in Sierra Leone
  • Ultimate Soccer League, Semi-professional indoor soccer league
  • United Soccer League, defunct U.S. soccer league active 1983–1984
  • United Soccer Leagues, the parent organization for the men's lower division leagues of US Soccer, as well as a women's league and a youth league
  • United States Lines, a defunct American shipping company
  • Social Liberal Union, a political alliance in Romania