Uroporphyrinogen III Decarboxylase

Uroporphyrinogen III Decarboxylase

Identifiers Symbols UROD; PCT; UPD External IDs OMIM: 613521 MGI: 98916 HomoloGene: 320 ChEMBL: 1681619 GeneCards: UROD Gene EC number 4.1.1.37

Gene Ontology
Molecular function	• uroporphyrinogen decarboxylase activity • ferrous iron binding
Cellular component	• nucleus • nucleolus • cytoplasm • cytosol • microtubule cytoskeleton
Biological process	• liver development • porphyrin-containing compound metabolic process • protoporphyrinogen IX biosynthetic process • heme biosynthetic process • response to iron ion • response to amine stimulus • response to estradiol stimulus • small molecule metabolic process • response to ethanol • uroporphyrinogen III metabolic process • response to mercury ion • response to methylmercury • response to fungicide • cellular response to arsenic-containing substance
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 7389 22275 Ensembl ENSG00000126088 ENSMUSG00000028684 UniProt P06132 P70697 RefSeq (mRNA) NM_000374.4 NM_009478.3 RefSeq (protein) NP_000365.3 NP_033504.2 Location (UCSC) Chr 1:
45.48 – 45.48 Mb Chr 4:
116.99 – 116.99 Mb PubMed search

Uroporphyrinogen decarboxylase, also known as UROD, is an enzyme that in humans is encoded by the UROD gene.