Uroporphyrinogen III Decarboxylase

Uroporphyrinogen III Decarboxylase

Identifiers Symbols UROD; PCT; UPD External IDs OMIM: 613521 MGI: 98916 HomoloGene: 320 ChEMBL: 1681619 GeneCards: UROD Gene EC number 4.1.1.37

Gene Ontology
Molecular function • uroporphyrinogen decarboxylase activity
• ferrous iron binding
Cellular component • nucleus
• nucleolus
• cytoplasm
• cytosol
• microtubule cytoskeleton
Biological process • liver development
• porphyrin-containing compound metabolic process
• protoporphyrinogen IX biosynthetic process
• heme biosynthetic process
• response to iron ion
• response to amine stimulus
• response to estradiol stimulus
• small molecule metabolic process
• response to ethanol
• uroporphyrinogen III metabolic process
• response to mercury ion
• response to methylmercury
• response to fungicide
• cellular response to arsenic-containing substance
Sources: Amigo / QuickGO
RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 7389 22275 Ensembl ENSG00000126088 ENSMUSG00000028684 UniProt P06132 P70697 RefSeq (mRNA) NM_000374.4 NM_009478.3 RefSeq (protein) NP_000365.3 NP_033504.2 Location (UCSC) Chr 1:
45.48 – 45.48 Mb Chr 4:
116.99 – 116.99 Mb PubMed search

Uroporphyrinogen decarboxylase, also known as UROD, is an enzyme that in humans is encoded by the UROD gene.

Read more about Uroporphyrinogen III Decarboxylase:  Function, Clinical Significance, Mechanism

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