UPF may refer to:
- Universitat Pompeu Fabra, a university in Spain
- Université de la Polynésie Française, a university in Tahiti
- United People's Front of Nepal, a political organization
- International Francophone Press Union, an association of Francophone journalists
- Unified Power Format, a file format for electronic power intent
- University Press of Florida
- Ultraviolet protection factor, a rating for sun protective clothing
- Universal Peace Federation, an organization of the Unification Church
- Union for France, an electoral coalition in France, 1992-1997.
- Union populaire française, a breakaway section of the French Communist Party