Development
The uncinate fasciculus has the longest period of development in terms of fractional anisotropy as it alone amongst the major white fibre tracks continues to develop beyond the age of 30.
It seems to be developmentally vulnerable. In 12 year-old males that were preterm, abnormalities measured by fractional anisotropy in the left anterior uncinate correlated with verbal IQ, full-scale IQ, and Peabody Picture Vocabulary Test-Revised scores. In 10 year-old children who have suffered socioemotional deprivation, the left uncinate fasciculus shows reduced fractional anisotropy compared to that in other children, and this might underlie their cognitive, socioemotional, and behavioral difficulties.
Read more about this topic: Uncinate Fasciculus
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—John Emerich Edward Dalberg, 1st Baron Acton (1834–1902)