Ubr5

UBR5

Identifiers Symbols UBR5; DD5; EDD; EDD1; HYD External IDs OMIM: 608413 MGI: 1918040 HomoloGene: 9295 GeneCards: UBR5 Gene

Gene Ontology
Molecular function	• RNA binding • ubiquitin-protein ligase activity • protein binding • zinc ion binding • ubiquitin-ubiquitin ligase activity • ubiquitin binding
Cellular component	• nucleus • cytoplasm
Biological process	• protein polyubiquitination • DNA repair • ubiquitin-dependent protein catabolic process • response to DNA damage stimulus • cell proliferation • positive regulation of protein import into nucleus, translocation • positive regulation of catenin import into nucleus • protein ubiquitination involved in ubiquitin-dependent protein catabolic process • progesterone receptor signaling pathway • positive regulation of canonical Wnt receptor signaling pathway • negative regulation of histone H2A K63-linked ubiquitination • negative regulation of double-strand break repair
Sources: Amigo / QuickGO

Orthologs Species Human Mouse Entrez 51366 70790 Ensembl ENSG00000104517 ENSMUSG00000037487 UniProt O95071 Q80TP3 RefSeq (mRNA) NM_015902 NM_001081359 RefSeq (protein) NP_056986 NP_001074828 Location (UCSC) Chr 8:
103.26 – 103.43 Mb Chr 15:
37.97 – 38.08 Mb PubMed search

E3 ubiquitin-protein ligase UBR5 is an enzyme that in humans is encoded by the UBR5 gene.