Ube2n

UBE2N

Identifiers Symbols UBE2N; UBC13; UbcH-ben; UbcH13 External IDs OMIM: 603679 MGI: 1934835 HomoloGene: 100734 ChEMBL: 6089 GeneCards: UBE2N Gene EC number 6.3.2.19

Gene Ontology
Molecular function	• ubiquitin-protein ligase activity • protein binding • ATP binding • ubiquitin binding
Cellular component	• ubiquitin ligase complex • nucleus • cytoplasm • cytosol • UBC13-MMS2 complex • UBC13-UEV1A complex
Biological process	• double-strand break repair via homologous recombination • DNA double-strand break processing • toll-like receptor signaling pathway • MyD88-dependent toll-like receptor signaling pathway • regulation of DNA repair • postreplication repair • cellular protein modification process • proteolysis • ubiquitin-dependent protein catabolic process • protein ubiquitination • histone ubiquitination • cytokine-mediated signaling pathway • positive regulation of histone modification • regulation of histone ubiquitination • toll-like receptor 2 signaling pathway • toll-like receptor 4 signaling pathway • toll-like receptor 5 signaling pathway • toll-like receptor 9 signaling pathway • toll-like receptor 10 signaling pathway • nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway • toll-like receptor TLR1:TLR2 signaling pathway • toll-like receptor TLR6:TLR2 signaling pathway • positive regulation of I-kappaB kinase/NF-kappaB cascade • innate immune response • positive regulation of DNA repair • T cell receptor signaling pathway • positive regulation of NF-kappaB transcription factor activity • positive regulation of ubiquitin-protein ligase activity • nucleotide-binding oligomerization domain containing signaling pathway • protein K63-linked ubiquitination
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 7334 93765 Ensembl ENSG00000177889 ENSMUSG00000074781 UniProt P61088 P61089 RefSeq (mRNA) NM_003348 NM_080560.3 RefSeq (protein) NP_003339 NP_542127.1 Location (UCSC) Chr 12:
93.8 – 93.84 Mb Chr 10:
94.98 – 95.01 Mb PubMed search

Ubiquitin-conjugating enzyme E2 N is a protein that in humans is encoded by the UBE2N gene.