Ube2b

UBE2B

Identifiers Symbols UBE2B; E2-17kDa; HHR6B; HR6B; RAD6B; UBC2 External IDs OMIM: 179095 MGI: 102944 HomoloGene: 101298 GeneCards: UBE2B Gene EC number 6.3.2.19

Gene Ontology
Molecular function	• ubiquitin-protein ligase activity • protein binding • ATP binding • ubiquitin protein ligase binding
Cellular component	• chromatin • nuclear chromatin • XY body • nucleus • replication fork • cytoplasm • plasma membrane • HULC complex
Biological process	• protein polyubiquitination • response to hypoxia • in utero embryonic development • DNA repair • postreplication repair • maintenance of chromatin silencing • ubiquitin-dependent protein catabolic process • protein monoubiquitination • response to DNA damage stimulus • spermatogenesis • sperm axoneme assembly • response to UV • positive regulation of reciprocal meiotic recombination • protein ubiquitination • cellular response to insulin stimulus • negative regulation of histone phosphorylation • histone H2A ubiquitination • response to drug • negative regulation of apoptotic process • proteasomal ubiquitin-dependent protein catabolic process • negative regulation of cAMP-mediated signaling • protein stabilization • chiasma assembly • protein autoubiquitination • canonical Wnt receptor signaling pathway • histone lysine demethylation • synaptonemal complex organization • protein K63-linked ubiquitination • protein K48-linked ubiquitination • protein K11-linked ubiquitination
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 7320 22210 Ensembl ENSG00000119048 ENSMUSG00000020390 UniProt P63146 P63147 RefSeq (mRNA) NM_003337 NM_009458 RefSeq (protein) NP_003328 NP_033484 Location (UCSC) Chr 5:
133.71 – 133.73 Mb Chr 11:
51.99 – 52 Mb PubMed search

Ubiquitin-conjugating enzyme E2 B is a protein that in humans is encoded by the UBE2B gene.