Ube2a

UBE2A

Identifiers Symbols UBE2A; HHR6A; MRXS30; MRXSN; RAD6A; UBC2 External IDs OMIM: 312180 MGI: 102959 HomoloGene: 68308 GeneCards: UBE2A Gene EC number 6.3.2.19

Gene Ontology
Molecular function	• ubiquitin-protein ligase activity • protein binding • ATP binding • ubiquitin protein ligase binding
Cellular component	• chromatin • nuclear chromatin • XY body • cytosol • HULC complex
Biological process	• protein polyubiquitination • in utero embryonic development • antigen processing and presentation of peptide antigen via MHC class I • DNA repair • postreplication repair • ubiquitin-dependent protein catabolic process • positive regulation of cell proliferation • response to UV • histone H2A ubiquitination • protein autoubiquitination • maternal process involved in female pregnancy • protein K48-linked ubiquitination • protein K11-linked ubiquitination
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 7319 22209 Ensembl ENSG00000077721 ENSMUSG00000016308 UniProt P49459 Q9Z255 RefSeq (mRNA) NM_003336 NM_019668 RefSeq (protein) NP_003327 NP_062642 Location (UCSC) Chr X:
118.71 – 118.72 Mb Chr X:
36.87 – 36.88 Mb PubMed search

Ubiquitin-conjugating enzyme E2 A is a protein that in humans is encoded by the UBE2A gene.