Ube1c

UBE1C

Identifiers Symbols UBA3; UBE1C; hUBA3 External IDs OMIM: 603172 MGI: 1341217 HomoloGene: 2951 GeneCards: UBA3 Gene

Gene Ontology
Molecular function	• protein binding • ATP binding • acid-amino acid ligase activity • ligand-dependent nuclear receptor binding • NEDD8 activating enzyme activity • protein heterodimerization activity
Cellular component	• nucleus
Biological process	• cellular protein modification process • proteolysis • endomitotic cell cycle • protein neddylation • negative regulation of transcription, DNA-dependent • regulation of cell cycle
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 9039 22200 Ensembl ENSG00000144744 ENSMUSG00000030061 UniProt Q8TBC4 Q8C878 RefSeq (mRNA) NM_003968 NM_001111106 RefSeq (protein) NP_003959 NP_001104576 Location (UCSC) Chr 3:
69.1 – 69.13 Mb Chr 6:
97.18 – 97.21 Mb PubMed search

E2 binding domain

appbp1-uba3-nedd8, an e1-ubiquitin-like protein complex with atp

Identifiers

Symbol

E2_bind

Pfam

PF08825

InterPro

IPR014929

Available protein structures:
Pfam	structures
PDB	RCSB PDB; PDBe
PDBsum	structure summary

NEDD8-activating enzyme E1 catalytic subunit is a protein that in humans is encoded by the UBA3 gene.