Disease
It has been shown that mutations in the U4atac snRNA can cause microcephalic osteodysplastic primordial dwarfism type I (MOPD I), also called Taybi-Linder syndrome (TALS). MOPD I is a developmental disorder that is associated with brain and skeletal abnormalities. It has been shown that the mutations cause defective U12 splicing.
Read more about this topic: U4atac Minor Spliceosomal RNA
Famous quotes containing the word disease:
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—Henry More (1614–1687)
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—Aldous Huxley (1894–1963)
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—Sarah Josepha Buell Hale 1788–1879, U.S. novelist, poet and women’s magazine editor. American Ladies Magazine, pp. 36-40 (December 1828)