TSB may refer to:
- Trustee Savings Bank, a UK Bank recently revived via a deal with Lloyds TSB and Co-op Banks
- Lloyds TSB, successor company to the Trustee Savings Bank in Great Britain.
- Permanent TSB, the retail banking division of Irish Life and Permanent and successor to the Trustee Savings Bank in the Republic of Ireland.
- (TSB Bank, formerly the Taranaki Savings Bank, a New Zealand-owned bank.
- Technical Service Bulletin, a recommended procedure for repairing a vehicle
- This S*$& Breaks, common term used on car forums in place of the "Technical Service Bulletin." aka, a recall.
- Tecmo Super Bowl
- Thiosymbescaline
- The Satanic Bible
- Tri State Bmx
- Transportation Safety Board of Canada
- Transportation Safety Bureau of Hungary
- The Saga Begins
- Treib–Seelisberg-Bahn, a funicular railway in the canton of Uri, Switzerland
- TV. Shinshu, a television station in Nagano Prefecture, Japan
- Popular ballad classification labels according to The Types of the Scandinavian Medieval Ballad, or that catalogue itself
- The TSB Orchestra, A band Based in Dayton, Ohio
- Technology Strategy Board
- Tryptic Soy Broth