T-cell Surface Glycoprotein CD3 Epsilon Chain

T-cell Surface Glycoprotein CD3 Epsilon Chain

Identifiers Symbols CD3E; T3E; TCRE External IDs OMIM: 186830 MGI: 88332 HomoloGene: 586 ChEMBL: 1975 GeneCards: CD3E Gene

Gene Ontology
Molecular function transmembrane signaling receptor activity
receptor signaling protein activity
SH3 domain binding
protein kinase binding
receptor signaling complex scaffold activity
T cell receptor binding
protein heterodimerization activity
Cellular component immunological synapse
plasma membrane
integral to plasma membrane
external side of plasma membrane
T cell receptor complex
alpha-beta T cell receptor complex
Biological process positive regulation of T cell anergy
protein complex assembly
cell surface receptor signaling pathway
transmembrane receptor protein tyrosine kinase signaling pathway
signal complex assembly
G-protein coupled receptor signaling pathway
response to nutrient
T cell costimulation
positive regulation of interferon-gamma production
positive regulation of interleukin-4 production
positive regulation of T cell proliferation
T cell activation
regulation of apoptotic process
negative thymic T cell selection
positive regulation of interleukin-2 biosynthetic process
negative regulation of smoothened signaling pathway
positive regulation of alpha-beta T cell proliferation
positive regulation of peptidyl-tyrosine phosphorylation
regulation of immune response
positive regulation of calcium-mediated signaling
T cell receptor signaling pathway
Sources: Amigo / QuickGO
RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 916 12501 Ensembl ENSG00000198851 ENSMUSG00000032093 UniProt P07766 P22646 RefSeq (mRNA) NM_000733 NM_007648 RefSeq (protein) NP_000724 NP_031674 Location (UCSC) Chr 11:
118.18 – 118.19 Mb Chr 9:
45 – 45.01 Mb PubMed search

CD3e molecule, epsilon also known as CD3E is a polypeptide which in humans is encoded by the CD3E gene which resides on chromosome 11.

Read more about T-cell Surface Glycoprotein CD3 Epsilon Chain:  Function, Clinical Significance, Interactions, See Also

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