Function
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development.
Read more about this topic: T-cell Surface Glycoprotein CD3 Epsilon Chain
Famous quotes containing the word function:
“For me being a poet is a job rather than an activity. I feel I have a function in society, neither more nor less meaningful than any other simple job. I feel it is part of my work to make poetry more accessible to people who have had their rights withdrawn from them.”
—Jeni Couzyn (b. 1942)
“Science has fulfilled her function when she has ascertained and enunciated truth.”
—Thomas Henry Huxley (1825–95)
“The function of comedy is to dispel ... unconsciousness by turning the searchlight of the keenest moral and intellectual analysis right on to it.”
—George Bernard Shaw (1856–1950)