Sowell is a surname. It may refer to:
- Anthony Sowell (born 1959), American serial killer
- Arnie Sowell, American middle distance runner
- Bobby Sowell, American musician
- Dawn Sowell, American sprinter
- Jerald Sowell, American football player
- Mary Harper Sowell, American poet
- Mike Sowell, American sports historian and professor of journalism
- Thomas Sowell, American economist, political commentator, and author
- Wayne Sowell, American politician
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