Incidence
Incidence of Sanfilippo syndrome varies geographically, with approximately 1 case per 280,000 live births in Northern Ireland, 1 per 66,000 in Australia, and 1 per 50,000 in the Netherlands.
The Australian study estimated the following incidences for each subtype of Sanfilippo syndrome:
| Sanfilippo syndrome type | Approximate incidence | Percentage of cases |
|---|---|---|
| A | 1 in 100,000 | 60% |
| B | 1 in 200,000 | 30% |
| C | 1 in 1,500,000 | 4% |
| D | 1 in 1,000,000 | 6% |
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