Salsa may refer to:
- Salsa (sauce), any of various sauces of Spanish, Italian or Latin American origin, from the Spanish or Italian word for sauce
- Salsa music, a fusion of Afro-Cuban musical styles based on the Cuban son
- Salsa (dance), the dance forms corresponding to salsa music
- Salsa (1988 film), a 1988 film based on the dance
- Salsa (2000 film), a 1999 film based on the dance
- Salsa (album), a 2000 album by Celia Cruz
- Salsa (fashion), a clothing company and brand
- In cryptography, the Salsa family of stream ciphers, particularly Salsa20
- SALSA (programming language), an actor based programming language
- SEAT Salsa, a concept car built by the Spanish car maker SEAT
- A character in the 2006 video game Mother 3
- A character in the 2007 XBOX360 and 2008 PlayStation 3 game Eternal Sonata
- Salsa d'Haiti a Haitian airline
- Salsa (satellite), also known as Cluster 2, an ESA satellite
- SALSA, Safe And Local Supplier Approval, a UK food and beverage supplier accreditation.