The restriction point (R) is a point in G1 of the animal cell cycle at which the cell becomes “committed” to the cell cycle, after which extracellular proliferation stimulants are no longer required.
Read more about Restriction Point: History of The Restriction Point, Extracellular Signals and The Restriction Point, Restriction-point Mechanism, Dynamics, The Restriction Point in Cancer
Famous quotes containing the words restriction and/or point:
“If we can find a principle to guide us in the handling of the child between nine and eighteen months, we can see that we need to allow enough opportunity for handling and investigation of objects to further intellectual development and just enough restriction required for family harmony and for the safety of the child.”
—Selma H. Fraiberg (20th century)
“If mothers are told to do this or that or the other,... they lose touch with their own ability to act.... Only too easily they feel incompetent. If they must look up everything in a book, they are always too late even when they do the right things, because the right things have to be done immediately. It is only possible to act at exactly the right point when the action is intuitive or by instinct, as we say. The mind can be brought to bear on the problem afterwards.”
—D.W. Winnicott (20th century)