The restriction point (R) is a point in G1 of the animal cell cycle at which the cell becomes “committed” to the cell cycle, after which extracellular proliferation stimulants are no longer required.
Read more about Restriction Point: History of The Restriction Point, Extracellular Signals and The Restriction Point, Restriction-point Mechanism, Dynamics, The Restriction Point in Cancer
Famous quotes containing the words restriction and/or point:
“If we can find a principle to guide us in the handling of the child between nine and eighteen months, we can see that we need to allow enough opportunity for handling and investigation of objects to further intellectual development and just enough restriction required for family harmony and for the safety of the child.”
—Selma H. Fraiberg (20th century)
“The ellipse is as aimless as that,
Stretching invisibly into the future so as to reappear
In our present. Its flexing is its account,
Return to the point of no return.”
—John Ashbery (b. 1927)