Background
The aromatic part of the quinine molecule is a quinoline with a methoxy substituent. The amine component has a quinuclidine skeleton and the methylene bridge in between has a hydroxyl group. The substituent at the carbon-3 position is a vinyl group. The molecule is optically active with four stereogenic groups making synthesis potentially difficult because it is one of 16 stereoisomers.
Read more about this topic: Quinine Total Synthesis
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