The acronym PVS may refer to:
- Project Vote Smart, Non-partisan information on U.S. federal and state candidates, ballot measures, issues and legislation.
- Persistent vegetative state
- Plummer-Vinson syndrome, a triad of esophageal webs, glossitis, and iron deficiency anemia
- Polynesian Voyaging Society
- Potato virus S
- Potentially visible set, a technique to precompute visibility in order to accelerate 3D rendering.
- The IATA code for Provideniya Bay Airport
- Principal variation search
- Prototype Verification System, a specification language used for the formal specification and verification of software
- PVS News, a satirical news channel on the BBC's programme Broken news
- Prisoner Visitation and Support, a prison-visitation program in the United States Federal and Military prisons
- Personal Viewing Sight with a numerical suffix to designate the model. PVS's are used by the American military for passive (non-thermal) night vision devices, such as PVS-14. PVS suffixes range from PVS-2 through PVS-22 skipping PVS-16. Most military PVS's have a civilian equivalent model number
- Polyvinyl siloxane, an addition reaction silicone elastomer used as impression material in Dentistry