Pedro Rodriguez or Pedro Rodríguez may refer to:
- Pedro Rodríguez (soldier) (1912–1999), Puerto Rican Korean War hero who won two Silver Star Medals
- Pedro Rodríguez (racing driver) (1940–1971), Mexican racing driver
- Pedro Rodriguez (NASA) (born 1953), Puerto Rican scientist and inventor in NASA
- Pedro Rodríguez (cyclist) (born 1966), Ecuadorian cyclist
- Pedro Rodríguez Ledesma (born 1987), Spanish footballer
- Pedro Rodríguez (politician) (1869–1932), Philippine politician
- Pedro Jesús Rodríguez (1907–1982), Chilean lawyer, academic and politician
- Pedro Rodríguez, Conde de Campomanes (1723–1802), Spanish statesman and writer
- Pedro Rodriguez (theologian), Spanish theologian
- Pedro Rodriguez de Miranda (1696–1766), Spanish painter of the late-Baroque period
- Pedro Rodríguez (motorcycle racer) (born 1994), Spanish Grand Prix motorcycle racer
- Pedro Rodríguez (water polo), Cuban water polo player who played Water polo at the 1980 Summer Olympics
- Pedro Rodríguez (athlete), Cuban shot putter who won in the Athletics at the 1926 Central American and Caribbean Games
- Pedro Rodríguez (cardinal), bishop of Burgos of the fourteenth century
- Pedro A. Rodríguez, PPD member of the 15th Legislative Assembly of Puerto Rico
- Pedro Rodríguez (weightlifter), Cuban weightlifter who won in the Weightlifting at the 1991 Pan American Games