Pe may refer to:
- Pe (Cyrillic), a letter (П) in the Cyrillic alphabet
- Pe (letter), a letter (פ, ف, etc.) in several Semitic alphabets
- Pe (Persian), this letter (پ) in the Arabic alphabet
- Weierstrass p (also called "pe"), a mathematical letter (℘) used in Weierstrass's elliptic functions and power sets
- Péclet number (abbreviated "Pe."), a dimensionless number used in physics
- Pe (text editor), a text editor for BeOS
- Pe, Tibet, a town on the Yarlung Tsangpo River
- Pe, one of two cities which merged into Buto
- .pe, the Internet country code top-level domain (ccTLD) for Peru
- Pulmonary emphysema, a lung disease.
- Pulmonary embolism
- Prince Edward Island, one of Canadas states
- Portable Executable, the Microsoft Windows executable format