PDS can refer to:
- Computing
- Panzer Dragoon Saga, a role-playing video game
- Partitioned data set, a type of dataset of IBM systems
- Processor Direct Slot, a slot found in some Macintosh computers
- Protocol Data Services, a British information technology services company
- Protected distribution system, a safeguarded telecommunication system
- Plant Design System, a 3D CAD application for Plant Design from Intergraph
- Medical
- Paroxysmal depolarizing shift, a pre-seizure interictal neuronal EEG spike in epilepsy.
- Parkinson's Disease Society of the UK, a British medical research charity dedicated to the support and curing of Parkinson's disease
- Pigment dispersion syndrome, an affliction of the eye
- Personal Demographics Service, a database of NHS patient demographic details
- Political parties
- Party of Democratic Socialism (Germany)
- Party of Democratic Socialism (India)
- Party of the Sicilians
- Progressive Democrats, a defunct political party of Ireland
- Democratic Party of the Left (Partito Democratico della Sinistra), a defunct political party of Italy
- Senegalese Democratic Party (Parti Démocratique Sénégalais), a political party of Senegal
- Sudanese Democratic Party (Parti Démocratique Soudanais), a defunct political party of Sudan
- Democratic Social Party (Partido Democrático Social), a defunct political party of Brazil
- Prosperous Peace Party (Partai Damai Sejahtera), a political party of Indonesia
- Parti de la Democratie Socialiste, a defunct provincial political party of Quebec, Canada
- Schools
- Princeton Day School, a private school in Princeton, New Jersey
- Peabody Demonstration School, a now-closed private school in Nashville, Tennessee
- Providence Day School, a private school in Charlotte, North Carolina
- Patumwan Demonstration School, Srinakharinwirot University, a public secondary school in Bangkok, Thailand
- Scientific
- Photothermal deflection spectroscopy, spectroscopy measuring the change in refractive index due to laser heating of a surface
- Planetary Data System, a system NASA uses for robotic mission data
- Polydioxanone
- Other
- Particularly dangerous situation, a high-end watch occasionally issued by the Storm Prediction Center
- Pound sterling, the currency of the United Kingdom
- Precision Drill Squad, a skilled military performance of Singapore
- Prinzhorn Dance School, a British alt/punk band
- Product design specification, a term used in product design
- Public Distribution System, a retail type system run by government to supply essential items to vulnerable sections of the society at reasonable (subsidized) prices
- Pineapple Dance Studios, a dance studio complex based in the Covent Garden area of central London, England
- Public Defender Service, a criminal law defence provider in England and Wales, part of the Legal Services Commission