PBR is a three-letter acronym that can refer to:
- Pabst Blue Ribbon, an American brand of beer
- Parti Burkinabè pour la Refondation
- Partition Boot Record, same as Volume Boot Record
- Patrol Boat, River, a type of river patrol boat used by the US Navy during the Vietnam War
- Pebble bed reactor, a type of nuclear reactor
- Peripheral Benzodiazepine Receptor
- Petrobras, a Brazilian oil company
- Photobioreactor
- Pilling-Bedworth ratio, a crystallographic ratio used to estimate if the metal is likely to passivate in dry air from creation of a protective oxide layer.
- Plant breeders' rights, a patented cultivar
- Plastic baton round, a type of non-lethal projectile more commonly known as the plastic bullet
- Point blank range
- Pokémon Battle Revolution, a video game for the Wii console
- Policy based routing
- Pre-Budget Report, one of the two economic forecasts that HM Treasury is required to deliver to the UK Parliament each year
- P/B ratio, a financial term used in company valuation, also known as Price to Book Ratio
- Precariously Balanced Rock or Balancing rock
- Professional Bull Riders, a sport, circuit, and company for professional bull riding
- Budget deficit, the amount a government expects to require in the financial year, also known as Public Borrowing Requirement
- Puffing Billy Railway, Melbourne, a narrow gauge tourist railway in Melbourne, Australia
- Performance based regulation, a regulation scheme