Nuclear magnetic resonance spectroscopy of proteins (usually abbreviated protein NMR) is a field of structural biology in which NMR spectroscopy is used to obtain information about the structure and dynamics of proteins. The field was pioneered by Richard R. Ernst and Kurt Wüthrich, among others. Protein NMR techniques are continually being used and improved in both academia and the biotech industry. Structure determination by NMR spectroscopy usually consists of several following phases, each using a separate set of highly specialized techniques. The sample is prepared, resonances are assigned, restraints are generated and a structure is calculated and validated.
Read more about Nuclear Magnetic Resonance Spectroscopy Of Proteins: Sample Preparation, Data Collection, Resonance Assignment, Restraint Generation, Hydrogen–deuterium Exchange, Structure Calculation, Structure Validation, Dynamics, NMR Spectroscopy On Large Proteins, Automation of The Process
Famous quotes containing the words nuclear, magnetic, resonance and/or proteins:
“The problems of the world, AIDS, cancer, nuclear war, pollution, are, finally, no more solvable than the problem of a tree which has borne fruit: the apples are overripe and they are falling—what can be done?... Nothing can be done, and nothing needs to be done. Something is being done—the organism is preparing to rest.”
—David Mamet (b. 1947)
“We are in great haste to construct a magnetic telegraph from Maine to Texas; but Maine and Texas, it may be, have nothing important to communicate.”
—Henry David Thoreau (1817–1862)
“It is closing time in the gardens of the West and from now on an artist will be judged only by the resonance of his solitude or the quality of his despair.”
—Cyril Connolly (1903–1974)
“Civilization means food and literature all round. Beefsteaks and fiction magazines for all. First-class proteins for the body, fourth-class love-stories for the spirit.”
—Aldous Huxley (1894–1963)