Neural Development - Synapse Elimination

Synapse Elimination

Several motorneurones compete for each neuromuscular junction, but only one survives until adulthood. Competition in vitro has been shown to involve a limited neurotrophic substance that is released, or that neural activity infers advantage to strong post-synaptic connections by giving resistance to a toxin also released upon nerve stimulation. In vivo it is suggested that muscle fibres select the strongest neuron through a retrograde signal.

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Famous quotes containing the word elimination:

    To reduce the imagination to a state of slavery—even though it would mean the elimination of what is commonly called happiness—is to betray all sense of absolute justice within oneself. Imagination alone offers me some intimation of what can be.
    André Breton (1896–1966)