The floor plate is a structure integral to the developing nervous system of vertebrate organisms. Located on the ventral midline of the embryonic neural tube, the floor plate is a specialized glial structure that spans the anteroposterior axis from the midbrain to the tail regions. It has been shown that the floor plate is conserved among vertebrates with homologous structures in invertebrates such as the fruit fly Drosophila and the nematode C. elegans. Functionally, the structure serves as an organizer to ventralize tissues in the embryo as well as to guide neuronal positioning and differentiation along the dorsoventral axis of the neural tube.
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Famous quotes containing the words floor and/or plate:
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—Unknown. The Wee Wee Man (l. 21–28)
“Then he rang the bell and ordered a ham sandwich. When the maid placed the plate on the table, he deliberately looked away but as soon as the door had shut, he grabbed the sandwich with both hands, immediately soiled his fingers and chin with the hanging margin of fat and, grunting greedily, began to much.”
—Vladimir Nabokov (1899–1977)