Murrell is a surname. It refers to:
- Persons
- Adrian Murrell (b. 1970), American professional football player
- Chris Murrell (contemporary), American jazz and gospel singer
- Frank Murrell (1874–1931), British businessman and politician from Avon County
- Hilda Murrell (1906–1984), English naturalist and campaigner against nuclear energy
- Ivan Murrell (1943–2006), American professional baseball player
- Jaime Murrell (contemporary), Panamanian musician
- Jana Murrell (contemporary), American beauty queen
- Joe Murrell (1879–1952), English cricketer
- John Murrell (c. 1806–c. 1845), legendary American bandit
- John Murrell (b. 1945), Canadian playwright
- Marques Murrell (b. 1985), American professional football player
- Red Murrell (b. 1912, unknown if still living), American western swing bandleader and guitarist
- Scott Murrell (contemporary), English rugby league player
- Sharon Murrell (contemporary), Canadian politician from Saskatchewan
- Other
- Murrell Home, historic home near Tahlequah, Oklahoma, USA
- Murrell River on East Falkland in the Falkland Islands