MME may stand for:

  • MME (psychedelic), 2,4-dimethoxy-5-ethoxyamphetamine, a psychedelic drug
  • Michigan Merit Exam, a minimum-competency test for students
  • Mitsubishi Motors Europe, the European subsidiary of Mitsubishi Motors
  • Membrane metallo-endopeptidase, an enzyme
  • Madam, a married woman
  • MME, the IATA code for Durham Tees Valley Airport, England
  • Mobility Management Entity, a standardized entity in a System Architecture Evolution network dedicated to mobility management
  • Mathematics & Mathematics Education, an academic group of the National Institute of Education, Nanyang Technological University, Singapore
  • Multimedia Extensions, an extension to Windows 3.0 to support multimedia
  • Midwest Motor Express, a less than truckload freight carrier based in Bismarck, North Dakota, United States