Methionine - Methionine Restriction

Methionine Restriction

There is scientific evidence that restricting methionine consumption can increase lifespans in some animals.

A 2005 study showed methionine restriction without energy restriction extends mouse lifespan.

On the other hand, a study published in Nature showed adding just the essential amino acid methionine to the diet of fruit flies under dietary restriction (DR - including restriction of essential amino acids) restored fecundity without reducing the lifespans that are typical of DR. Restored to normal levels, "Methionine alone increased fecundity as much as full feeding, but without reducing lifespan."

Several studies showed that methionine restriction also increases lifespan, inhibits aging-related disease processes, and inhibits colon carcinogenesis in rats.

A 2009 study on rats showed "methionine supplementation in the diet specifically increases mitochondrial ROS production and mitochondrial DNA oxidative damage in rat liver mitochondria offering a plausible mechanism for its hepatotoxicity".

Read more about this topic:  Methionine

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