Mein may refer to:
- Mein clan, an ethnic group living along the Forcados River in Delta State, Nigeria
- Mein (noodles), a variety of Chinese noodles made from wheat
- Mein (song), a song by the band Deftones and System of a Down singer Serj Tankian
- Écoust-Saint-Mein, a commune in the Pas-de-Calais department in France
- John Gordon Mein (1913-1968), a United States ambassador to Guatemala, the first to be assassinated while in service
- Will G. Mein (1866 -19?), a British book illustrator who flourished in the late 19th to early 20th century
- William Mein Smith, (1799-1869), a key actor in the early settlement of New Zealand's capital city, Wellington