Role in The Cell Cycle
During G1 and S phase, the CDK1 subunit of MPF is inactive due to an inhibitory enzyme, Wee1. Wee1 phosphorylates the Thr-14 and Tyr-15 residues of CDK1, rendering MPF inactive. During the transition of G2 to M phase, MPF inhibits Wee1, resulting in a positive feedback loop.
Read more about this topic: Maturation Promoting Factor
Famous quotes containing the words role in, role, cell and/or cycle:
“So successful has been the camera’s role in beautifying the world that photographs, rather than the world, have become the standard of the beautiful.”
—Susan Sontag (b. 1933)
“The role of the writer is not simply to arrange Being according to his own lights; he must also serve as a medium to Being and remain open to its often unfathomable dictates. This is the only way the work can transcend its creator and radiate its meaning further than the author himself can see or perceive.”
—Václav Havel (b. 1936)
“It is plain that there is no separate essence called courage, no cup or cell in the brain, no vessel in the heart containing drops or atoms that make or give this virtue; but it is the right or healthy state of every man, when he is free to do that which is constitutional to him to do.”
—Ralph Waldo Emerson (1803–1882)
“The lifelong process of caregiving, is the ultimate link between caregivers of all ages. You and I are not just in a phase we will outgrow. This is life—birth, death, and everything in between.... The care continuum is the cycle of life turning full circle in each of our lives. And what we learn when we spoon-feed our babies will echo in our ears as we feed our parents. The point is not to be done. The point is to be ready to do again.”
—Paula C. Lowe (20th century)